Ders: Evrimsel Biyolojide Deney ve Kuram İlişkisi

İçerik: Evrimsel deneylere giriş. Soyoluş ve analizi, soyoluşsal yöntemle antik gen canlandırma.

Ders notları için: TIKLAYIN

Kaynaklar: 

 Atasal gen oluş turma:

• A new method of inference of ancestral nucleotide and amino acid sequences, Yang Z, Kumar S, Nei M, Genetics. 1995; (4):1641-50
• Experimental Phylogenetics – Generation of a Known Phylogeny, Hillis DM, Bull JJ, White ME, Badgett MR, Molineux IJ, Science. 1992; 255 (5044): 589-592
• Reconstructing contiguous regions of an ancestral genome, Ma J, Zhang L, Suh BB, digerleri & Miller W, Genome Res. 2006; (12):1557-65
• Evolution of hormone-receptor complexity by molecular exploitation, Bridgham JT, Carroll SM, Thornton JW, Science. 2006, 312(5770):97-101
• Assessing the accuracy of ancestral sequence protein reconstruction methods, Williams PD, Pollock DD, Blackburne BP, Goldstein RA, PLoS Comput. Biol. 2006, 2(6):e69
• Molecular paleoscience: systems biology from the past, Benner SA, Sassi SO, Gaucher EA, Adv Enzymol Relat Area Mol Biol. 2007; 75:1-132

Deneysel Evrim:

• Microbial genetics: Evolution experiments with microorganisms: the dynamics and genetic bases

of adaptation, Elena SF, Lenski RE, Nat Rev Genet. 2003; 4:457-469

• Historical contingency and the evolution of a key innovation in an experimental population of Escherichia coli, Blount ZD, Lenski RE, Proc Natl Acad Sci. 2008; 105(23): 7899-7906